We're into four added minutes as City close in on yet another victory – their fifth straight will extend their best winning run of the campaign so far.
90'
Since scoring the fourth goal it's largely become a game of keep-ball for Manchester City, who are oozing class at the moment. Southampton simply can't get near them.
86'
Gundogan's cross-field pass is played back by Walker to Silva, but his ball for Alvarez at the back post is headed clear by Bednarek.
85'
Walker recovers well after losing possession to Perraud on the far touchline, but is shoved directly over the sideline by the Southampton left-back who concedes a cheap free-kick in the process.
83'
De Bruyne aims a low cross towards Silva, but the ball takes a deflection on the edge of the box and rolls back to Bazunu in the Saints' goal.
81'
Sergio Gómez enters the game and replaces N. Aké.
K. Phillips enters the game and replaces Rodri.
Kalvin Phillips also enters proceedings, and he'll replace Rodri at the base of City's dominant midfield.
City also make late changes, with Ake coming off for summer signing Sergio Gomez to see out the game.
80'
I. Diallo enters the game and replaces R. Lavia.
R. Perraud enters the game and replaces T. Walcott.
Walcott is also replaced late on by Ruben Selles, with left-back Romain Perraud replacing the striker in what appears to be damage limitation for the hosts.
Maitland-Niles has been down injured for some time, but won't be coming off after being cleared to continue. Lavia does though, with the former Manchester City academy product replaced by Ibrahima Diallo.
75'
Penalty goal scored by J. Álvarez for Manchester City!
GOOOOAAALL!!! Gap restored, as quick as a flash! Alvarez steps up for City, and with one of his first touches of the ball, sends Bazunu the wrong way and slots his penalty into the bottom-right corner! 4-1 now, and that Mara goal a moment ago now looks like scant consolation for Southampton.
72'
S. Mara has scored a goal for Southampton! Assist by M. Djenepo.
GOOOOOAAAALLL!!! Saints score straight away!!! They've only just come on, but what a combination between the substitutes! Djenepo jinks in and away from three City defenders on his way into the box, and squares for Mara to slot home superbly! 3-1, and could that give the hosts a slight chance of a comeback here?
The dancing feet from Djenepo there were something to behold, with that glimpse of hope for the Saints almost entirely down to the Malian winger's quick feet.
Minute
Description
69'
M. Djenepo enters the game and replaces C. Alcaraz.
J. Álvarez enters the game and replaces E. Haaland.
S. Mara enters the game and replaces K. Sulemana.
Alcaraz also comes off for the hosts, with Moussa Djenepo on to see out the final 20 minutes.
Southampton ring the changes following another City goal, as Sekou Mara replaces the lively Sulemana in attack for the Saints.
He's on a hat-trick, but Haaland won't get the chance to add his third, as he comes off for World Cup winner Julian Alvarez to replace him up front.
68'
E. Haaland has scored a goal for Manchester City! Assist by J. Grealish.
GOOOOOAAAALLL!!!! What a finish!!! Grealish dribbles down the left before cutting inside and sticking up a cross for Haaland. The ball's slightly behind him, but that doesn't matter to the Norwegian, who jumps to smash a flying bicycle kick into the bottom corner, and just like that, City lead by three! 3-0 to City, and 30 league goals for Haaland - what a player this young man is!
Grealish had the freedom of Hampshire to stroll into the box there, and a well-timed cross was converted into a sensational goal by the City number nine.
65'
Grealish dances beyond both Ward-Prowse and Maitland-Niles before floating a cross into the middle, where Bella-Kotchap rises to head behind for another City corner. City prepare to take their eighth corner of the match, with Southampton still yet to win one.
64'
Walker's looping cross from the right isn't met cleanly by either Haaland or Maitland-Niles, and Bazunu races off his line to smother the bouncing ball before the former can pounce.
62'
Walker-Peters' advanced run is halted on the edge of City's box, leaving Saints open at the back as the visitors launch a counter-attack. De Bruyne crosses from the byline looking for Haaland at the back post, but Bednarek climbs high to head the ball behind for a corner.
61'
S. Armstrong enters the game and replaces M. Elyounoussi.
Elyounoussi comes off following City's second goal, and Stuart Armstrong enters the fray for the final half hour.
58'
J. Grealish has scored a goal for Manchester City!
GOOOOAAALLL!!! City make it two!! De Bruyne's pass in behind is met by Grealish bursting into the box, but the winger's left-footed finish is well saved by Bazunu! The goalkeeper doesn't push the ball out far enough though, and Grealish is on hand to slot the ball past him with the outside of his foot, giving City a 2-0 lead and Southampton a mountain to climb!
56'
Bernardo Silva enters the game and replaces R. Mahrez.
K. Walker enters the game and replaces J. Stones.
E. Haaland gets yellow.
Ward-Prowse slips in midfield, almost letting De Bruyne and Haaland take advantage. He recovers to find Bella-Kotchap, who is flattened on halfway by Haaland after releasing the ball, with the City goalscorer shown a yellow card by the referee.
City make their first changes of the game, with the first seeing Mahrez replaced by Bernardo Silva in attack.
Stones is also brought off by Pep Guardiola, and his England team-mate Kyle Walker will come on in his place.
54'
Elyounoussi dispossesses Stones in midfield and sets off on the break. Lavia is fouled, but Saints play advantage and Elyounoussi's effort from the edge of the box is blocked.
49'
Ward-Prowse whips a deep free-kick into the City box, but Bella-Kotchap can't cleanly connect with the ball in the air, and his header bounces behind for a goal kick.
47'
Gundogan makes a late burst in the box to latch onto Grealish's pass, but his attempted ball across the face of goal is put behind for a corner by Bednarek.
46'
Walcott resumes proceedings for Saints, and we're back under way in this second-versus-bottom clash.
45' +3
HALF-TIME: SOUTHAMPTON 0-1 MANCHESTER CITY
45' +1
We're into two additional minutes at St Mary's, with City having taken the lead at the best possible time.
45'
E. Haaland has scored a goal for Manchester City! Assist by K. De Bruyne.
A perfect ball in from De Bruyne, putting the delivery into an area that made it easier for Haaland to score than miss.
GOOOOOAAAALLL!!! There he is, and there it is for City!! One ball into the area doesn't come off, but De Bruyne isn't deterred as Grealish finds him in space on the left. His in-swinging cross has Haaland right underneath it, and the ruthless Norwegian nods past Bazunu to put City 1-0 up!! He's been restricted to scraps for much of this half, but once Haaland gets an inkling of a chance, it never takes him long to finish it off!
43'
Dias picks out Grealish with a long diagonal ball to the left, but Maitland-Niles shadows the winger once again and City win another corner.
40'
De Bruyne's clipped pass over the top aims to release Haaland in behind, but the Norwegian's loose touch allows the ball to bounce into Bazunu's gloves.
39'
Stones advances up the right and drills a low cross into the box. Numbers arrive at the near post, but Bednarek puts the ball behind for City's fifth corner of the match. Saints are yet to win one of their own.
36'
J. Stones gets yellow.
Stones loses possession in midfield and races back to make amends. Alcaraz steps away from the City defender but is caught by Stones' sliding challenge, for which he's penalised and shown the game's first yellow card.
34'
Grealish brings down a high ball and looks to cut inside, but he catches Lavia in the stomach with a high knee and concedes the free-kick.
32'
City's fourth corner of the game is fired to the back post, where Gundogan's header is an easy one for Bazunu to catch and hold at his near post.
31'
Grealish looks to return a pass to De Bruyne in behind Ward-Prowse, but the ball appears to strike the Saints captain on his hand, inside the box. The referee's got a good view, and although replays do clearly show the ball striking his arm, there's no intentional contact and play-on is signalled.
30'
Quick feet and frenetic pace takes Sulemana past a flailing Akanji, but the winger's cross is behind Elyounoussi and Walker-Peters can't make anything of it!
28'
Grealish is again caught down that left-hand side, this time marginally late by Maitland-Niles, and the home crowd are far from happy as the referee awards City a free-kick.
26'
Grealish is down following a mid-air collision with Bednarek, and play halts for the England playmaker to receive treatment, though he's soon back to his feet.
24'
Maitland-Niles wins the ball high up the field, but City's defence holds firm and Ake forces a throw in the far-side corner.
20'
After Sulemana's attempted low cross into the box is hooked away by Stones, Elyounoussi fires the ball back into the area and almost finds Alcaraz before the ball whistles beyond the far post.
19'
Elyounoussi plays a ball down the left channel for Sulemana to chase, but Dias slides across and wins possession back as cleanly as you like!
15'
Grealish slips De Bruyne in behind Maitland-Niles, but the on-loan Arsenal defender blocks the Belgian's cross behind for another City corner. Bazunu punches the delivery clear, and a follow-up shot from Gundogan is deflected wide!
13'
De Bruyne and Mahrez both attempt crosses into the box, but returning centre-back Bella-Kotchap stands tall to head the respective efforts away from danger.
11'
Grealish is crowded out and so switches play to the right. Mahrez receives and crosses to the back post, where Maitland-Niles heads behind to give City their first corner of the match.
5'
A heavy touch from Ederson almost sees him dispossessed by Alcaraz, but Akanji arrives to give the goalkeeper an outlet and the danger is averted.
3'
An early Southampton free-kick is headed clear by City, but Elyounoussi flashes another ball into the box and across the face of goal, before the offside flag is raised against Sulemana.
1'
City captain Gundogan kicks the game off, and we're up and running on the south coast of England.
Bottom-placed Southampton have taken just one point from their last three league games, and although a victory over the defending champions would lift them off the bottom of the table, they’d still be a point off safety as this ridiculously tight Premier League relegation battle continues.
City trail league leaders Arsenal by eight points with a game in hand, and having not lost any of their last seven games, winning the last four straight, Pep Guardiola’s side will be confident they can close the gap with the Gunners still to face Liverpool on Sunday.
SOUTHAMPTON (4-2-3-1): Gavin Bazunu; Ainsley Maitland-Niles, Jan Bednarek, Armel Bella-Kotchap, Kyle Walker-Peters; James Ward-Prowse, Romeo Lavia; Mohamed Elyounoussi, Carlos Alcaraz, Kamaldeen Sulemana; Theo Walcott.
Hello, and welcome to live coverage of this fixture in the Premier League, as bottom side Southampton take on title-chasing Manchester City at St Mary’s Stadium.
SUBS: Alex McCarthy, Duje Caleta-Car, Paul Onuachu, Romain Perraud, Stuart Armstrong, Sekou Mara, Moussa Djenepo, Samuel Edozie, Ibrahima Diallo.
MANCHESTER CITY (3-2-4-1): Ederson; Manuel Akanji, Ruben Dias, Nathan Ake; John Stones, Rodri; Riyad Mahrez, Kevin De Bruyne, Ilkay Gundogan, Jack Grealish; Erling Haaland.
Here come the teams, and we're ready and raring to go at a sunlit St Mary's!
The teams are back on the St Mary's pitch for the second half, and can the hosts find an equaliser to get themselves firmly back into this game?
That's all from us, we hope you enjoyed the game. Until the next one rolls around, it's bye for now.
A 4-1 defeat leaves Southampton firmly in the mire, rock-bottom of the table and four points from safety, with their goal difference also taking a negative hit in this game. It's going to take something very special for them to escape from here, but with a logjam of teams separated by very few points above them, anything is possible in the last eight games. City, on the other hand, have nine games left in their pursuit of a third consecutive Premier League title, and performances as ruthless as the one we've seen at St Mary's will give them every chance of chasing down Arsenal to achieve it.
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