Argentine clubs River Plate and Lanus booked their Copa Sudamericana spots in the next round, with contrasting aggregate victories.
River Plate trailed Ecuadorian outfit LDU Loja 2-1 after their first leg in Ecuador, with their away goal meaning a 1-0 win would have got the Argentines over the line.
And when Teofilo Gutierrez struck on 36 minutes, the game was on the terms of Ramon Diaz River Plate side.
Manuel Lanzini wrapped up the aggregate victory with a well-struck goal in the 71st minute, to win the leg 2-0 for the hosts in Buenos Aires.
Lanus were already virtually assured of a last-eight spot after a 4-0 first leg win over Universidad de Chile, and on their second-leg trip to Santiago, they limited the damage to a 1-0 loss.
Charles Aranguiz scored the winning goal in the leg for Universidad de Chile on 69 minutes.
In this week's first leg encounters, Coritiba blew their home leg against Itagui, slumping to a 1-0 loss.
The Brazilian hosts were trumped by a goal in the first minute after the half-time interval, as Yessi Mena fired the Colombian visitors a valuable away goal.
Fellow Brazil Serie A side Sport Recife were beaten 2-0 away to Libertad, with first-half goals to Gustavo Gomez and Pedro Benitez handing the Paraguayans a handy lead at the tie's midway point.
There was better news for Brazilian club Ponte Preta, who opened up a two-goal advantage late in their 2-0 win over Colombian outfit Deportivo Pasto.
Fellipe Bastos struck deep into second-half injury time, to follow up Uendel's opener on 31 minutes for the hosts in Sao Paulo.
City rivals Sao Paulo were held to a 1-1 home stalemate by Chilean club Universidad Catolica, while an own goal from Bahia midfielder Diones handed a 1-0 win to Colombia's Atletico Nacional in Medellin.
|10||M. Lanzini||64' 71'|
|Coach: R. Díaz|
for C. Ledesma 46'
for A. Rojas 46'
for F. Andrada 80'
|Blanc: Barca are the model for PSG|
|Newcastle just need three more points - Janmaat|
|Gaya: Six finals left for Valencia|
|Muller wary of Porto counter-attacks|
|Bartomeu plays down Pogba link|
|Verratti hails ´essential´ Ibrahimovic|
|Zidane backs PSG to upset Barca|
|America v Montreal Impact: Klopas unfazed by host´s form|
|Vlaar open to Villa stay|
|Shepherd urges fans not to boycott Newcastle|
|Maritimo 1 Nacional 1: Tiquinho ensures derby finishes all square|
|Fiorentina 0 Verona 1: Diamanti and Neto pay the penalty|
|Elche 1 Real Sociedad 0: Bergara gifts win to hosts|
|Van Persie returns in Under-21 game|
|Turkish Super Lig Review: Galatasaray slip sees Fenerbahce go top|
|Russian Premier League Review: Arsenal Tula and Rostov maintain survival bids|
|Frontzeck named as Korkut´s replacement at Hannover|
|Lopetegui wary of Bayern backlash|
|Pastore plays down Cantona´s world best tag|
|PSG absences no excuse for failure - Blanc|
|Suarez sad to see Gerrard leaving Liverpool|
|Cleber injury adds to Hamburg woes|
|Northern Ireland free to play Romania at Windsor Park|
|Juve sweating on Vidal availability|
|Monaco v Juventus: Evra ready to take control|
|Striking concerns for Chelsea after Drogba injury|
|PSG and Chelsea have bid for Dybala, claims agent|
|Pogba can leave Juve for ´right offer´|
|Bendtner dropped after arriving late for training|
|Messi achievement unrepeatable, says Luis Enrique|
|Football League Preview: Preston and MK Dons battling to join Bristol City|
|Real Madrid v Atletico Madrid: Ancelotti optimistic amid injury concerns|
|Iniesta declared fit for PSG second leg|
|Bale remains a doubt for Atletico clash|
|Schweinsteiger set to face Porto, Ribery to miss out|
|No broken cheekbone for Silva|
|Final appearance can remove negativity at Villa - Fox|
|Bale selected in Football League Team of the Decade|
|PSV director: United and PSG want Depay|
|Korkut sacked by relegation-threatened Hannover|
|Sherwood: Pressure all on Arsenal|
|Newcastle in a ´dangerous moment´ - Colback|
|Kovac hopes to have Modric fit for Euro qualifier|
|Copa Libertadores Preview: Cruzeiro boss Oliveira does not fear sack|
|MLS Review: Revs extend unbeaten run, Timbers stun City|
|Fournier proud and disappointed|
|Shaw ready to make an impact|
|Hazard among best three in the world - Mourinho|
|Carver: Newcastle are in relegation battle|
|CAF Champions League Review: Setif get two away goals, Al Ahly denied late on|
|Inzaghi praises Milan derby officials|
|La Liga Review: Granada frustrate Sevilla, Villarreal´s woes continue|
|Inter should have had a penalty, Mancini fumes|
|Ligue 1 Review: Lyon return top after derby draw|
|Inter 0 Milan 0: Disappointing derby ends in stalemate|
|Primeira Liga Review: Sporting made to battle, Penafiel running out of time|
|Balotelli targets officials in latest social media outburst|
|Bundesliga Review: Werder Bremen edge Nordderby, De Bruyne rescues Wolfsburg|
|Serie A Review: Napoli close on stumbling Roma|
|Pochettino congratulates 30-goal Kane|
|Rodgers questions Liverpool´s mental strength|
|Carver counting on experience after latest defeat|
|Sherwood marvels at Grealish potential|
|Eredivisie Review: Dordrecht relegated as Go Ahead Eagles stun Feyenoord|
|Newcastle United 1 Tottenham 3: Losing streak continues amid fan boycott|
|Kouyate elbow on Silva accidental - Allardyce|
|Aston Villa 2 Liverpool 1: Delph ends Gerrard´s hopes of dream farewell|
|Pellegrini hails City response to derby defeat|
|Silva back home after Kouyate elbow|
|Manchester City 2 West Ham 0: Silva injury sours routine win|
|Bayern Munich v Porto: Neuer rallies Germans for uphill battle|
|Barcelona v Paris Saint-Germain: Marquinhos keeps the faith ahead of Camp Nou test|
|Fer closes in on QPR return|
|Crouch set for surgery|
|Dortmund confirm Tuchel as Klopp replacement|
|Adams leaves relegation-threatened Tranmere|
|Real still unsure over Modric injury|
|Tevez rubbishes Juve exit talk|
|Moyes: I had to fight to keep Rooney at United|
|Perth Glory 3 Melbourne City 1: Maclaren treble the difference|
|Dyche: Burnley are too honest|
|Illarramendi eager for Real stay|
|Hazard issues Chelsea warning|
|MLS Review: Injury-time winner buoys Galaxy, Martins shows class for Sounders|
|Pastore talents ´unpredictable´ - Blanc|
|Liverpool much bigger than City - Rodgers|
|AFC Champions League Preview: Evergrande look to progress|
|Clarke expects distraught Federici to bounce back|
|Toure is City´s scapegoat - agent|
|Allegri praises high-flying Juve|
|Athletic Bilbao 4 Getafe 0: Hosts end winless run|